Boceprevir vs Sildenafil

Interacting Drugs
Boceprevir
vs
Sildenafil
Security Level
Moderate, Consider therapy modification
Mechanism
Sildenafil: CYP3A4 Inhibitors (Strong) may increase the serum concentration of Sildenafil.
Management
When used for treatment of pulmonary arterial hypertension, use of sildenafil with strong CYP3A4 inhibitors should be avoided. When used for erectile dysfunction, starting dose should be reduced to 25 mg. Max dose with ritonavir is 25 mg per 48 hours.

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Other Interactions of Boceprevir

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Other Interactions of Sildenafil

We are Developing Our database, More results coming soon.

Boceprevir vs Sildenafil

Interacting Drugs
Boceprevir
vs
Sildenafil
Security Level
Major, Avoid combination
Mechanism
Sildenafil: Boceprevir may increase the serum concentration of Sildenafil.
Management
Avoid sildenafil when used for treatment of pulmonary arterial hypertension in patients receiving boceprevir. Sildenafil for erectile dysfunction should be limited to 25 mg every other day with close monitoring for sildenafil toxicity.

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Other Interactions of Boceprevir

We are Developing Our database, More results coming soon.

Other Interactions of Sildenafil

We are Developing Our database, More results coming soon.