Boceprevir vs Dexamethasone (Systemic)

Interacting Drugs
Boceprevir
vs
Dexamethasone (Systemic)
Security Level
Moderate, Consider therapy modification
Mechanism
Dexamethasone (Systemic): May decrease the serum concentration of Boceprevir.
Management
Concomitant use of boceprevir and dexamethasone should be avoided if possible due to possible diminished therapeutic effects of boceprevir. If the combination cannot be avoided, closely monitor response to boceprevir.

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