Boceprevir vs Colchicine

Interacting Drugs
Boceprevir
vs
Colchicine
Security Level
Moderate, Consider therapy modification
Mechanism
Colchicine: CYP3A4 Inhibitors (Strong) may increase the serum concentration of Colchicine.
Management
Colchicine is contraindicated in patients with impaired renal or hepatic function who are also receiving a strong CYP3A4 inhibitor. In those with normal renal and hepatic function, reduce colchicine dose as directed.

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