Aluminum hydroxide, magnesium hydroxide, and simethicone vs Ursodiol

Interacting Drugs
Aluminum hydroxide, magnesium hydroxide, and simethicone
vs
Ursodiol
Security Level
Moderate, Consider therapy modification
Mechanism
Ursodiol: Aluminum Hydroxide may decrease the serum concentration of Ursodiol.
Management
Consider administration of ursodiol 2 hours before or 6 hours after aluminum-containing antacid products to prevent adsorption in the gastrointestinal tract.

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