Aluminum hydroxide, magnesium hydroxide, and simethicone vs Itraconazole

Interacting Drugs
Aluminum hydroxide, magnesium hydroxide, and simethicone
vs
Itraconazole
Security Level
Moderate, Consider therapy modification
Mechanism
Itraconazole: Antacids may decrease the serum concentration of Itraconazole.
Management
Administer itraconazole at least 1 hour after and 2 hours before administration of any antacids. Itraconazole oral suspension may be less sensitive to the effects of decreased gastric acidity.

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