Aluminum hydroxide, magnesium hydroxide, and simethicone vs Gabapentin

Interacting Drugs
Aluminum hydroxide, magnesium hydroxide, and simethicone
vs
Gabapentin
Security Level
Moderate, Consider therapy modification
Mechanism
Gabapentin: Antacids may decrease the serum concentration of Gabapentin.
Management
Administer gabapentin at least 2 hours after antacid administration. Monitor patients closely for evidence of reduced response to gabapentin therapy when both of these drugs are being used.

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