Aluminum hydroxide, magnesium hydroxide, and simethicone vs Erlotinib

Interacting Drugs
Aluminum hydroxide, magnesium hydroxide, and simethicone
vs
Erlotinib
Security Level
Moderate, Consider therapy modification
Mechanism
Erlotinib: Antacids may decrease the serum concentration of Erlotinib.
Management
Separate the administration of erlotinib and any antacid by several hours in order to minimize the risk of a significant interaction.

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