Aliskiren and hydrochlorothiazide vs Allopurinol

Interacting Drugs
Aliskiren and hydrochlorothiazide
vs
Allopurinol
Security Level
Minor, Monitor Therapy
Mechanism
Allopurinol: Thiazide Diuretics may enhance the potential for allergic or hypersensitivity reactions to Allopurinol. Thiazide Diuretics may increase the serum concentration of Allopurinol. Specifically, Thiazide Diuretics may increase the concentration of Oxypurinol, an active metabolite of Allopurinol.
Management
Monitor therapy

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