Adefovir vs Tenofovir

Interacting Drugs
Adefovir
vs
Tenofovir
Security Level
Moderate, Consider therapy modification
Mechanism
Tenofovir: Adefovir may diminish the therapeutic effect of Tenofovir. Specifically, adefovir-associated mutations in Hepatitis B viral reverse transcriptase may decrease viral susceptibility to tenofovir. Tenofovir may increase the serum concentration of Adefovir. Similarly, Adefovir may increase the concentration of Tenofovir.
Management
Consider therapy modification

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Other Interactions of Tenofovir

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