Interacting Drugs |
Acetaminophen, chlorpheniramine, phenylephrine, and phenyltoloxamine vs Metyrapone |
Security Level |
 |
Mechanism |
Metyrapone: May increase the serum concentration of Acetaminophen. More importantly, by inhibiting the conjugative metabolism of acetaminophen, metyrapone may shift the metabolism towards the oxidative route that produces a hepatotoxic metabolite. |
Management |
Monitor therapy |
Acetaminophen, chlorpheniramine, phenylephrine, and phenyltoloxamine vs Metyrapone
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Other Interactions of Acetaminophen, chlorpheniramine, phenylephrine, and phenyltoloxamine
Other Interactions of Metyrapone
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