Acetaminophen and phenyltoloxamine vs SORAfenib

Interacting Drugs
Acetaminophen and phenyltoloxamine
vs
SORAfenib
Security Level
Moderate, Consider therapy modification
Mechanism
SORAfenib: Acetaminophen may enhance the hepatotoxic effect of SORAfenib. SORAfenib may increase the serum concentration of Acetaminophen.
Management
Consider therapy modification

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