Abiraterone vs CYP2D6 Substrates

Interacting Drugs
Abiraterone
vs
CYP2D6 Substrates
Security Level
Moderate, Consider therapy modification
Mechanism
CYP2D6 Substrates: Abiraterone Acetate may increase the serum concentration of CYP2D6 Substrates.
Management
Avoid concurrent use of abiraterone with CYP2D6 substrates that have a narrow therapeutic index whenever possible. When concurrent use is not avoidable, monitor patients closely for signs/symptoms of toxicity.

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Other Interactions of Abiraterone

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Other Interactions of CYP2D6 Substrates

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