Voglibose

Indications
Oral
Diabetes mellitus
Adult: 200-300 mcg tid.
Elderly: Initiate at lower doses.
Contraindications
Inflammatory bowel disease; GI obstruction or patients predisposed to it; conditions which may deteriorate as a result of increased gas formation eg, hernia; severe ketosis; diabetic coma or pre-coma; severe infection; hypersensitivity; pregnancy; lactation. Not to be used as monotherapy in IDDM.
Warnings / Precautions
History of laparotomy or ileus. Roemheld's syndrome, stenosis, severe hepatic or renal impairment. Child <18 yr; elderly. Monitor LFT. Treat hypoglycaemic episodes with glucose (not with sucrose).
Adverse Reactions
Flatulence; abdominal distension; diarrhoea; pain; skin reactions; hypoglycemia; increased LFT.
Potentially Fatal: Hepatotoxicity.
Drug Interactions
May enhance effects of other antidiabetics including insulin.
See Below for More voglibose Drug Interactions
Mechanism of Actions
Voligbose has general properties similar to acarbose and selectively inhibits α-glucosidase in the enteric canal, delaying the digestion and absorption of carbohydrate, thereby suppressing sharp increase in post-prandial plasma glucose.
Administration
Should be taken with food. (Take just before meals.)
Storage Conditions
Oral: Store below 30°C.
ATC Classification
A10BF03 - voglibose ; Belongs to the class of alpha glucosidase inhibitors. Used in the treatment of diabetes.
Storage
Oral: Store below 30°C.
Available As
  • Voglibose 0.2 mg
  • Voglibose 0.3 mg
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