Triprolidine

Indications
 Oral
Allergic conditions
Adult: 2.5 mg every 4-6 hr. Max: 10 mg daily.
Child: 4 mth-<2 yr: 0.313 mg every 4-6 hr; max: 1.252 mg daily. 2-<4 yr: 0.625 mg every 4-6 hr; max: 2.5 mg daily. 4-<6 yr: 0.938 mg every 4-6 hr; max: 3.744 mg daily. 6-<12 yr: 1.25 mg every 4-6 hr; max: 5 mg daily. ≥12 yr: 2.5 mg every 4-6 hr; max: 10 mg daily.
Contraindications
 Hypersensitivity to acrivastine; child < 4 mth; lactation.
Warnings / Precautions
 Angle-closure glaucoma; urinary retention; prostatic hypertrophy; pyloroduodenal obstruction; epilepsy. May impair ability to drive or operate machinery. Broken or eczematous skin (topical use). Child <6 yr should take only under the direction of a physician. Elderly, pregnancy.
Adverse Reactions
 CNS depression, headache, psychomotor impairment, dry mouth, thickened respiratory tract secretions, blurred vision, urinary difficulty or retention, constipation, increased gastric reflux, nausea, vomiting, diarrhoea, epigastric pain, myalgia, paraesthesias, extrapyramidal effects, tremor, sleep disturbances, depression, confusion, tinnitus, hypotension and hair loss.
Potentially Fatal: Blood dyscrasias.
Overdose Reactions
 Symptoms: Antimuscarinic, extrapyramidal and CNS side effects. In children or elderly, very often, CNS stimulation predominates over CNS depression and causes ataxia, excitement, tremors, psychoses, hallucinations, convulsions, hyperpyrexia, cardiorespiratory collapse and coma. In adults, CNS depression predominates and results in drowsiness, coma, convulsions, respiratory failure and CV collapse.
Drug Interactions
 Increased sedation with CNS depressants eg, alcohol, barbiturates, hypnotics, opioid analgesics, anxiolytics, sedatives and antipsychotics. Increased antimuscarinic side effects with other antimuscarinic drugs e.g. atropine, TCA and MAOI. May mask signs of ototoxicity caused by aminoglycosides.
See Below for More triprolidine hydrochloride Drug Interactions
Mechanism of Actions
 Triprolidine is an antihistamine derived from alkylamine that has antimuscarinic and mild sedative effects. May also be used in fixed dose combination with pseudoephedrine hydrochloride.
Distribution: Distributed into breast milk.
Metabolism: A carboxylated derivative makes up about half of the dose excreted in the urine.
Excretion: Excreted via urine as metabolites. Reported half life: 3-5 hr or more.
Administration
 May be taken with or without food.
Storage Conditions
 Oral: Store between 15-30°C.
ATC Classification
 R06AX07 - triprolidine ; Belongs to the class of other antihistamines for systemic use.
Storage
 Oral: Store between 15-30°C.
Available As
  • Triprolidine 0.625 mg
  • Triprolidine 1.25 mg
  • Triprolidine 2.5 mg
  • Triprolidine 25 mg

    • Subscribe for latest updates

    Subscribe to our e-mail newsletter to receive updates.

    No comments yet.

    Post Review about Triprolidine


    Triprolidine Containing Brands

    We are Developing Our database, More results coming soon.

    Triprolidine is used in following diseases

    We are Developing Our database, More results coming soon.

    Drug - Drug Interactions of Triprolidine

    We are Developing Our database, More results coming soon.