Trimetazidine

Indications
Oral
Angina pectoris, Meniere's disease
Adult: As conventional tab: 40-60 mg daily in divided doses.
Contraindications
Hypersensitivity. Pregnancy and lactation.
Adverse Reactions
GI disturbances, vomiting, nausea.
Mechanism of Actions
Trimetazidine is a cellular acting anti-ischaemic agent. It has 3 main properties by which it acts as a cytoprotective agent. It inhibits the anaerobic glycolysis and fatty acid metabolism, thus allowing only aerobic glycolysis. This action helps to restore the energy balance in the cell. It inhibits acidosis and free radical accumulation in the cell. All these action help the cell to restore the normal ionic and metabolic balance.
Absorption: Rapidly absorbed. Peak plasma concentration: within 2 hr (conventional tab); 5 hr (modified release).
Excretion: Via urine, mainly as unchanged drug. Half life: 6 hr (conventional); 7 hr (modified release).
Administration
Should be taken with food.
Storage Conditions
Oral: Store below 30°C.
ATC Classification
C01EB15 - trimetazidine ; Belongs to the class of other cardiac preparations.
Storage
Oral: Store below 30°C.
Available As
  • Trimetazidine 20 mg
  • Trimetazidine 35 mg
  • Trimetazidine 40 mg
  • Trimetazidine 60 mg
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    Trimetazidine Containing Brands

    Click on Prescription information to see Indications ( Uses ), Contraindications, Prescription information of respective Constituents.

    Brand Name Manufacturer Unit/Price Package unit/Price Constituents/Unit
    Tablet Cardimax (20 mg) USV-Corvette (US Vitamins Ltd) 1 Tablet
    ₹ 3.70
    10 Tablet
    ₹ 37.00
  • More Information Trimetazidine 20 mg
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    Tablet Eldon (20 mg) Lancer Pharmaceuticals (P) Ltd. 1 Tablet
    ₹ 3.00
    10 Tablet
    ₹ 30.00
  • More Information Trimetazidine 20 mg
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    Tablet Guard (20 mg) Admac Pharma Ltd. 1 Tablet
    ₹ 3.60
    10 Tablet
    ₹ 36.00
  • More Information Trimetazidine 20 mg
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    Tablet Isvedon (20 mg) Life Medicare & Biotech Pvt. Ltd. 1 Tablet
    ₹ 3.50
    10 Tablet
    ₹ 35.00
  • More Information Trimetazidine 20 mg
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    Tablet Mayosest (20 mg) Otsira Genetica (Aristo Pharmaceuticals Pvt Ltd.) 1 Tablet
    ₹ 3.52
    10 Tablet
    ₹ 35.23
  • More Information Trimetazidine 20 mg
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    Tablet Mayozest (20 mg) Otsira Genetica (Aristo Pharmaceuticals Pvt Ltd.) 1 Tablet
    ₹ 3.51
    10 Tablet
    ₹ 35.13
  • More Information Trimetazidine 20 mg
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    Tablet Metacard (20 mg) IPCA Laboratories Ltd. 1 Tablet
    ₹ 3.20
    10 Tablet
    ₹ 32.00
  • More Information Trimetazidine 20 mg
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    Tablet Myovedon (20 mg) Argus (Aurobindo Pharma Ltd.) 1 Tablet
    ₹ 3.60
    10 Tablet
    ₹ 36.00
  • More Information Trimetazidine 20 mg
  • See Brands having above combination
    Suspension Septabid (50 ml) Emcure Pharmaceuticals Ltd. 5 ml
    ₹ 1.00
    50 ml
    ₹ 10.02
  • More Information Sulphamethoxazole 200 mg
  • More Information Trimetazidine 40 mg
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    Tablet Triguard (20 mg) Select (FDC Limited) 1 Tablet
    ₹ 2.92
    10 Tablet
    ₹ 29.20
  • More Information Trimetazidine 20 mg
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    Trimetazidine is used in following diseases

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    Drug - Drug Interactions of Trimetazidine

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