Indications |
Oral Spasticity, Muscle spasms Adult: As hydrochloride: 50-150 mg tid. Child: As hydrochloride: <6 yr: 5 mg/kg daily in 3 divided doses; 6-14 yr: 2-4 mg/kg daily in 3 divided doses. |
Contraindications |
Myasthenia gravis. |
Adverse Reactions |
Muscular weakness, headache, hypotension, nausea, vomiting, abdominal discomfort. |
Mechanism of Actions |
Tolperisone is a centrally acting muscle relaxant. Absorption: Well absorbed from GI tract. Peak plasma concentration in 0.5-1 hr. Bioavailability: 20%. Metabolism: Extensively metabolised by liver and kidney. Elimination half-life (IV): 1.5 hr. Excretion: Excreted mainly via urine as metabolites. |
Administration |
Should be taken with food. |
ATC Classification |
M03BX04 - tolperisone ; Belongs to the class of other centrally-acting muscle relaxants. |
Available As |
|
Tolperisone
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Drug - Drug Interactions of Tolperisone
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