Tolperisone

Indications
Oral
Spasticity, Muscle spasms
Adult: As hydrochloride: 50-150 mg tid.
Child: As hydrochloride: <6 yr: 5 mg/kg daily in 3 divided doses; 6-14 yr: 2-4 mg/kg daily in 3 divided doses.
Contraindications
Myasthenia gravis.
Adverse Reactions
Muscular weakness, headache, hypotension, nausea, vomiting, abdominal discomfort.
Mechanism of Actions
Tolperisone is a centrally acting muscle relaxant.
Absorption: Well absorbed from GI tract. Peak plasma concentration in 0.5-1 hr. Bioavailability: 20%.
Metabolism: Extensively metabolised by liver and kidney. Elimination half-life (IV): 1.5 hr.
Excretion: Excreted mainly via urine as metabolites.
Administration
Should be taken with food.
ATC Classification
M03BX04 - tolperisone ; Belongs to the class of other centrally-acting muscle relaxants.
Available As
  • Tolperisone 100 mg
  • Tolperisone 150 mg
  • Tolperisone 450 mg
  • Tolperisone 50 mg
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    Tolperisone Containing Brands

    Click on Prescription information to see Indications ( Uses ), Contraindications, Prescription information of respective Constituents.

    Brand Name Manufacturer Unit/Price Package unit/Price Constituents/Unit
    Tablet Myotop (150 mg)
    Zuventus Health Care Ltd. 1 Tablet
    ₹ 7.90
    10 Tablet
    ₹ 79.00
  • More Information Tolperisone 150 mg
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    Tablet Synaptol (100 mg)
    Sun Pharmaceutical Industries Ltd. 1 Tablet
    ₹ 5.70
    10 Tablet
    ₹ 57.00
  • More Information Tolperisone 100 mg
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    Tablet Synaptol (150 mg)
    Sun Pharmaceutical Industries Ltd. 1 Tablet
    ₹ 7.20
    10 Tablet
    ₹ 72.00
  • More Information Tolperisone 150 mg
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    Tablet Synaptol (50 mg)
    Sun Pharmaceutical Industries Ltd. 1 Tablet
    ₹ 4.00
    10 Tablet
    ₹ 40.00
  • More Information Tolperisone 50 mg
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    Tablet Tolflex (150 mg)
    E.Merck (India) Ltd., 1 Tablet
    ₹ 8.73
    10 Tablet
    ₹ 87.25
  • More Information Tolperisone 150 mg
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    Tablet Tolfree (100 mg)
    Zydus Cadila Healthcare Ltd 1 Tablet
    ₹ 4.96
    10 Tablet
    ₹ 49.55
  • More Information Tolperisone 100 mg
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    Tablet Tolfree (150 mg)
    Zydus Cadila Healthcare Ltd 1 Tablet
    ₹ 7.33
    10 Tablet
    ₹ 73.30
  • More Information Tolperisone 150 mg
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    Tablet Tolifast (150 mg)
    Lupin Laboratories Ltd. 1 Tablet
    ₹ 7.90
    10 Tablet
    ₹ 79.00
  • More Information Tolperisone 150 mg
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    Tablet Tolpidol FC (150 mg)
    Themis Medicare Ltd. 1 Tablet
    ₹ 7.20
    10 Tablet
    ₹ 72.00
  • More Information Tolperisone 150 mg
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    Tablet Tolpidol FC (50 mg)
    Themis Medicare Ltd. 1 Tablet
    ₹ 4.00
    10 Tablet
    ₹ 40.00
  • More Information Tolperisone 50 mg
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    Tolperisone is used in following diseases

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