Indications |
Intramuscular As anabolic after debilitating illness Adult: As decanoate: 25-100 mg once every 3-4 wk. Intramuscular Postmenopausal osteoporosis Adult: As decanoate: 25-100 mg once every 3-4 wk. Intramuscular Metastatic breast cancer Adult: As decanoate: 25-100 mg once every 3-4 wk. Intramuscular Anaemia of chronic renal failure Adult: As decanoate: 50-200 mg wkly. Intramuscular Anaemia in chemotherapy patients Adult: 50-150 mg wkly. |
Contraindications |
Prostatic or breast carcinoma (male); nephrosis, porphyria; infants, pregnancy and lactation. |
Warnings / Precautions |
Monitor diabetic patients carefully. Conditions influenced by oedema (e.g. CV disease, migraine, seizure disorder, renal impairment). Hepatic impairment. Elderly. Discontinue if signs of virilisation in women occur. Monitor skeletal maturation in children. |
Adverse Reactions |
Male: Postpubertal: Acne, gynaecomastia, bladder irritability, priapism, insomnia, chills, decreased libido, hepatic dysfunction, nausea, diarrhoea, prostatic hyperplasia. Prepubertal: Acne, virilism, chills, insomnia, hyperpigmentation, diarrhoea, nausea. Female: Virilism, hypercalcaemia, nausea, diarrhoea, chills, insomnia, iron deficiency anaemia, hepatic dysfunction. |
Drug Interactions |
May increase effects of oral anticoagulants, insulin, oral antidiabetic agents, adrenal steroid, adrenocorticotropic hormone (ACTH). See Below for More nandrolone Drug Interactions |
Lab Interactions |
May alter glucose tolerance tests. |
Mechanism of Actions |
Nandrolone is an anabolic steroid. It promotes tissue-building processes and protein anabolism. It also stimulates erythropoeitin production, causing an increase in haemoglobin and RBC volume. Onset: 3-6 mth. Duration: Up to 30 days. Absorption: 77% (IM). Metabolism: Hepatic. Excretion: Via urine. |
ATC Classification |
S01XA11 - nandrolone ; Belongs to the class of other ophthalmologicals. A14AB01 - nandrolone ; Belongs to the class of estren derivative anabolic steroids used as systemic anabolic agents. |
Available As |
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Nandrolone
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Drug - Drug Interactions of Nandrolone
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