Indications |
Nasal Eradication of nasal colonisation with Staphylococci aureus Adult: As 2% nasal ointment: Apply into each nostril bid-tid for a max of 7 days. After application, the nostrils should be closed by pressing together and releasing the sides of the nose. Child: Adolescents (≥12 yr): Apply nasal ointment to the inner surface of both nostrils 2-3 times daily for 5-14 days. After application, the nostrils should be closed by pressing together and releasing the sides of the nose for approximately 1 min. Topical/Cutaneous Impetigo Adult: Apply a 2% ointment tid for 10 days. If no improvement is seen after 3-5 days, consider alternative treatment. Child: Apply a 2% ointment tid for 10 days. If no improvement is seen after 3-5 days, consider alternative treatment. Topical/Cutaneous Secondary skin infections Adult: Apply a 2% cream tid for 10 days. If no improvement is seen after 3-5 days, consider alternative treatment. Child: Apply a 2% ointment tid for 10 days. If no improvement is seen after 3-5 days, consider alternative treatment. |
Contraindications |
Hypersensitivity to mupirocin or polyethylene glycol. |
Warnings / Precautions |
Mucosal surfaces of eye; renal impairment; extensive burns or open wounds. Pregnancy, lactation, children <3 mth. |
Adverse Reactions |
Burning, stinging, pain, itching, erythema, dryness, tenderness, dermatitis and rash. |
Mechanism of Actions |
Mupirocin inhibits protein synthesis of the bacteria by binding to isoleucyl transfer RNA-synthetase. It is active against gram-positive and some gram-negative bacteria. Absorption: Minimal systemic absorption through intact skin (<0.3%). Distribution: Protein-binding: 95% Metabolism: Hepatic, converted to monic acid. Excretion: Urine; 17-36 min (elimination half-life). |
Storage Conditions |
Nasal: Store at or below 25°. Do not freeze. Topical/Cutaneous: Store at or below 25°. Do not freeze. |
ATC Classification |
D06AX09 - mupirocin ; Belongs to the class of other topical antibiotics used in the treatment of dermatological diseases. R01AX06 - mupirocin ; Belongs to the class of other nasal preparations for topical use. |
Storage |
Nasal: Store at or below 25°. Do not freeze. Topical/Cutaneous: Store at or below 25°. Do not freeze. |
Available As |
|
Mupirocin
Post Review about Mupirocin Click here to cancel reply.
Mupirocin Containing Brands
Mupirocin is used in following diseases
Drug - Drug Interactions of Mupirocin
Latest News
- FDA approves Ruconest for treatment of hereditary angioedema
- FDA recommend against aspirin to prevent First Heart Attacks
- FDA approves Pomalyst (pomalidomide) for advanced multiple myeloma
- FDA approves three new drug treatments for type 2 diabetes
- Long-term consequences of vaginal delivery on the pelvic floor
No comments yet.