Menadione

Indications
Oral
Vitamin K deficiency
Adult: 10 mg every 6 hr.
Oral
Severe hypoprothrombinaemia
Adult: 10 mg 3-4 times daily.
Intravenous
Vitamin K deficiency
Adult: 0.03 mcg/kg/day.
Child: Infants: 1-5 mcg/kg/day.
Intramuscular
Severe hypoprothrombinaemia
Adult: 2.5-10 mg daily.
Warnings / Precautions
Pregnancy. G6PD deficiency, vitamin E deficiency. Neonates, premature infants. Hepatic impairment. Monitor prothrombin time.
Adverse Reactions
Facial flushing, sweating, chest constriction/pain, dyspnoea, cyanosis, CV collapse. IM: Severe shock-like reactions, phlebitis, inj site reactions.
Potentially Fatal: Anaphylaxis.
Drug Interactions
Decreases effects of oral anticoagulants.
See Below for More menadione Drug Interactions
Mechanism of Actions
Menadione is a synthetic lipid-soluble vitamin K analogue. It is an essential cofactor in the hepatic synthesis of prothrombin (factor II) and other blood clotting factors (factors VII, IX, X and proteins C and S), and in the function of proteins important for bone development (e.g. osteocalcin).
Absorption: Requires bile for absorption from the GI tract.
Distribution: Accumulates in the liver; does not appear to cross the placenta.
ATC Classification
B02BA02 - menadione ; Belongs to the class of vitamin K. Used in the treatment of hemorrhage.
Available As
  • Menadione 0.1 mg
  • Menadione 0.13 mg
  • Menadione 0.5 mg
  • Menadione 0.56 mg
  • Menadione 0.66 mg
  • Menadione 1 mg
  • Menadione 10 mg
  • Menadione 15 mg
  • Menadione 20 mg
  • Menadione 5 mg
  • Menadione 66.20 mg
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    Menadione Containing Brands

    Click on Prescription information to see Indications ( Uses ), Contraindications, Prescription information of respective Constituents.

    Brand Name Manufacturer Unit/Price Package unit/Price Constituents/Unit
    Capsule Acrovitaplex Acron Pharmaceuticals 1 Capsule
    ₹ 1.50
    10 Capsule
    ₹ 15.00
  • More Information Folic Acid (Vit B9) 1.5 mg
  • More Information Pyridoxine 3 mg
  • More Information Riboflavin 10 mg
  • More Information Thiamine 10 mg
  • More Information Vit B12 15 mcg
  • More Information Vit C 150 mg
  • More Information Niacinamide 100 mg
  • More Information Vit D3 1000 iu
  • More Information Vit A 10000 iu
  • More Information Vit E 15 iu
  • More Information Menadione 0.1 mg
  • More Information Di-Calcium Phosphate 100 mg
  • More Information D-Panthenol 10 mg
  • See Brands having above combination
    Tablet Cadisper C Cadila Pharmaceuticals Ltd. 1 Tablet
    ₹ 1.31
    10 Tablet
    ₹ 13.10
  • More Information Vit C 100 mg
  • More Information Adrenochrome Monosemicarbazone 1 mg
  • More Information Dibasic Calcium Phosphate 100 mg
  • More Information Menadione 20 mg
  • More Information Rutin 60 mg
  • More Information Methyl Hesperdin 40 mg
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    Tablet CKP Bell Pharma Pvt. Ltd. 1 Tablet
    ₹ 1.31
    10 Tablet
    ₹ 13.08
  • More Information Vit C 75 mg
  • More Information Rutin 100 mg
  • More Information Carbazochrome 2.5 mg
  • More Information Dibasic Calcium Phosphate 100 mg
  • More Information Menadione 10 mg
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    Tablet Cyltabs Solvay Pharma India Pvt Ltd 1 Tablet
    ₹ 1.01
    10 Tablet
    ₹ 10.12
  • More Information Vit B12 1 mcg
  • More Information Vit A 2500 iu
  • More Information Vit D3 200 iu
  • More Information Vit B1 1 mg
  • More Information Vit C 30 mg
  • More Information Vit E 5 iu
  • More Information Niacinamide 15 mg
  • More Information Vit B2 2 mg
  • More Information Vit B6 0.5 mg
  • More Information Calcium Pantothenate 1 mg
  • More Information Folic Acid (Vit B9) 0.2 mg
  • More Information Potassium Sulphate 275 mcg
  • More Information Calcium Fluoride 325 mcg
  • More Information Dried Ferrous Sulphate 16.75 mg
  • More Information Liver Derived 200 mg
  • More Information Sodium Tauroglycocholate 50 mg
  • More Information Manganese Sulphate 1.35 mg
  • More Information Zinc Sulphate 75 mcg
  • More Information Menadione 1 mg
  • More Information Calcium Dibasic Phosphate 200 mg
  • More Information Potassium Iodide 65 mcg
  • More Information Copper Sulphate 2.5 mcg
  • More Information Ammonium Molybdate 5 mcg
  • More Information Magnesium Sulphate 1.25 mg
  • See Brands having above combination
    Capsule Gystat Comed Chemicals Pvt Ltd 1 Capsule
    ₹ 1.26
    10 Capsule
    ₹ 12.60
  • More Information Vit C 75 mg
  • More Information Tribasic Calcium Phosphate 144.43 mg
  • More Information Ferrous Gluconate 67 mg
  • More Information Citrus Bioflavonoid 150 mg
  • More Information Menadione 0.56 mg
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    Tablet Medostyp Medi Products Pvt.Ltd. 1 Tablet
    ₹ 1.73
    10 Tablet
    ₹ 17.29
  • More Information Vit C 100 mg
  • More Information Adrenochrome Monosemicarbazone 0.35 mg
  • More Information Menadione 15 mg
  • More Information Rutin 75 mg
  • See Brands having above combination
    Capsule Prenatal Wyeth Ltd. 1 Capsule
    ₹ 0.50
    60 Capsule
    ₹ 29.83
  • More Information Niacinamide 20 mg
  • More Information Vit A 2000 iu
  • More Information Folic Acid (Vit B9) 0.3 mg
  • More Information Thiamine 2 mg
  • More Information Riboflavin 2 mg
  • More Information Cyanocobalamin 1 mcg
  • More Information Ascorbic Acid 35 mg
  • More Information Dibasic Calcium Phosphate 400 mg
  • More Information Manganese Sulphate 0.369 mg
  • More Information Menadione 0.5 mg
  • More Information Dried Ferrous Sulphate 20.4 mg
  • More Information Chlolecalciferol 200 iu
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    Tablet Siochrome Albert David Limited 1 Tablet
    ₹ 1.33
    10 Tablet
    ₹ 13.30
  • More Information Vit C 150 mg
  • More Information Calcium Phosphate 200 mg
  • More Information Menadione 20 mg
  • More Information Adrenochrome Monosemicarbazone 0.5 mg
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    Tablet Stypindon (50+25+5) Zydus Cadila Healthcare Ltd 1 Tablet
    ₹ 0.20
    10 Tablet
    ₹ 2.00
  • More Information Vit C 50 mg
  • More Information Menadione 5 mg
  • More Information Rutin 25 mg
  • See Brands having above combination
    Tablet Styptindon (50+25+5) Indo Pharma Laboratory 1 Tablet
    ₹ 0.20
    10 Tablet
    ₹ 2.00
  • More Information Vit C 50 mg
  • More Information Menadione 5 mg
  • More Information Rutin 25 mg
  • See Brands having above combination
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    Menadione is used in following diseases

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    Drug - Drug Interactions of Menadione

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