Ferrous Gluconate

Indications
Oral
Iron-deficiency anaemia
Adult: Expressed in terms of elemental iron. Treatment: 60 mg bid up to 60 mg 4 times daily. Prevention: 60 mg daily.
Child: Expressed in terms of elemental iron. Treatment: Severe: 4-6 mg/kg/day in 3 divided doses; Mild to moderate: 3 mg/kg/day in 1-2 divided doses. Prevention: 1-2 mgkg/day.
Contraindications
Haemochromatosis, haemolytic anemia.
Warnings / Precautions
Avoid in patients with peptic ulcer, enteritis, or ulcerative colitis and those who receive frequent blood transfusions. Not to be used in premature infants until the vitamin E stores (deficient at birth) are replenished. Avoid prolonged treatment (>6 mth) except in patients with continuous menorrhagia or bleeding.
Adverse Reactions
GI symptoms e.g. stomach cramping, constipation, nausea, vomiting, dark stools, heartburn, diarrhea, teeth staining, urine discoloration.
Overdose Reactions
Overdose may lead to severe iron toxicity, espcially in children.
Drug Interactions
Concurrent admin with antacids/H2 antagonists may reduce absorption of iron. Chloramphenicol may delay response to iron. Iron may reduce the absorption of levodopa, methyldopa and penicillamine when given together. Absorption may be reduced when used with quinolones or tetracyclines. Concurrent admin with vitamin C may increase iron absorption.
See Below for More ferrous gluconate Drug Interactions
Lab Interactions
May cause false-positive for blood in stool by the guaiac test.
Food Interactions
Cereals, dietary fiber, tea, coffee, eggs and milk may reduce iron absorption.
Mechanism of Actions
Ferrous gluconate is used in the prevention and treatment of iron-deficiency anaemia. It replaces iron found in haemoglobin, myoglobin and enzymes. It also allows transportation of oxygen via haemoglobin.
Onset: Haematologic response: Oral: 3-10 days.
Administration
Should be taken on an empty stomach. (Best taken on an empty stomach. May be taken w/ meals to reduce GI discomfort.)
ATC Classification
B03AA03 - ferrous gluconate ; Belongs to the class of oral iron bivalent preparations. Used in the treatment of anemia.
Available As
  • Ferrous Gluconate 0.175 gm
  • Ferrous Gluconate 0.4 mg
  • Ferrous Gluconate 10 mg
  • Ferrous Gluconate 100 mg
  • Ferrous Gluconate 125 mg
  • Ferrous Gluconate 129.5 mg
  • Ferrous Gluconate 150 mg
  • Ferrous Gluconate 16 mg
  • Ferrous Gluconate 17 mg
  • Ferrous Gluconate 17.14 mg
  • Ferrous Gluconate 173 mg
  • Ferrous Gluconate 2 mg
  • Ferrous Gluconate 200 mg
  • Ferrous Gluconate 23 mg
  • Ferrous Gluconate 25 mg
  • Ferrous Gluconate 250 mg
  • Ferrous Gluconate 259 mg
  • Ferrous Gluconate 26 mg
  • Ferrous Gluconate 3 mg
  • Ferrous Gluconate 3.75 mg
  • Ferrous Gluconate 30 mg
  • Ferrous Gluconate IP 300 mg
  • Ferrous Gluconate 300 mg
  • Ferrous Gluconate 325 mg
  • Ferrous Gluconate 350 mg
  • Ferrous Gluconate 375 mg
  • Ferrous Gluconate 40 mg
  • Ferrous Gluconate 400 mg
  • Ferrous Gluconate 5 mg
  • Ferrous Gluconate 50 mg
  • Ferrous Gluconate IP 50 mg
  • Ferrous Gluconate 57 mg
  • Ferrous Gluconate 6.5 mg
  • Ferrous Gluconate 60 mg
  • Ferrous Gluconate 600 mg
  • Ferrous Gluconate 66 mg
  • Ferrous Gluconate 67 mg
  • Ferrous Gluconate 7.76 mg
  • Ferrous Gluconate 75 mg
  • Ferrous Gluconate 86.3 mg
  • Ferrous Gluconate 9 mg
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