Diptheria Toxoid

Indications
 Intramuscular
Primary immunisation
Adult: As a combination product with tetanus and inactivated poliomyelitis: 3 doses of each 0.5 ml at intervals of 1 mth, booster dose of 0.5 ml after 5 yr, repeated 10 yr later.
Child: 2 mth-10 yr: As a combination product with tetanus, pertussis (acellular), inactivated poliomyelitis and adsorbed haemophilus type B conjugate: 3 doses of 0.5 ml at intervals of 1 mth. >10 yr: As a combination product with tetanus and inactivated poliomyelitis: 3 doses of each 0.5 ml at intervals of 1 mth, booster dose of 0.5 ml after 5 yr, repeated 10 yr later.
Contraindications
 Hypersensitivity. Severe primary immunodeficiency. During or within 6 mth of stopping chemotherapy or radiotherapy treatment. Solid organ transplant and receiving immunosuppressants. Bone marrow transplant and within 12 mth of stopping immunosuppressive treatment. Patients receiving and within 3 mth of stopping high-dose systemic corticosteroids treatment. Immunosuppressed HIV positive patients.
Warnings / Precautions
 If alcohol or disinfectant is used for cleansing skin, ensure that it has evaporated before vaccination to prevent inactivation of live vaccines.
Adverse Reactions
 Hypersensitivity. Induration, sterile abscess or local reaction, possibly with inflammation or lymphangitis at the inj site. Fever, headache and malaise.
Potentially Fatal: Anaphylaxis.
Drug Interactions
 Live vaccines should normally be given at least 3 wk before or at least 3 mth after the use of immunoglobulin. Patients on immunosuppressants e.g. corticosteroids or antineoplastics may display reduced response to vaccines.
See Below for More vaccine, diphtheria toxoid Drug Interactions
Mechanism of Actions
 Diphtheria vaccines are used for active immunisation against diphtheria. The non-adsorbed vaccine has poor immunogenic properties and its effects are enhanced by admin as an adsorbed preparation. It is often used in combination with other vaccines e.g. tetanus toxoid.
ATC Classification
 J07AF01 - diphtheria toxoid ; Belongs to the class of diphtheria bacterial vaccines.
Available As
  • Diptheria Toxoid
  • Diptheria Toxoid –
  • Diptheria Toxoid 2.5 LF
  • Diptheria Toxoid 20 LF
  • Diptheria Toxoid 25 LF
  • Diptheria Toxoid 25 mcg
  • Diptheria Toxoid 30 iu
  • Diptheria Toxoid 50 LF

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