Difluprednate

Indications	Topical/Cutaneous Corticosteroid-responsive dermatoses *Adult:* Apply a thin layer of 0.02-0.05% cream, gel, oint over affected areas as directed.
Contraindications	Infectious dermatoses.
Warnings / Precautions	Glaucoma, infection. Avoid applying to broken skin or under occlusive dressings to prevent systemic absorption effects.
Adverse Reactions	Skin thinning when applied under occlusion. Folliculitis, hypertrichosis, skin atrophy, superinfection, stretch mark, loss of skin collagen and SC atrophy, local depigmentation, acne, burning sensation, pruritus, chronic glaucoma. Telangiectasia and purpura.
Mechanism of Actions	Difluprednate is a topical corticosteroid with glucocorticoid activity. It exhibits anti-inflammatory and immunosuppressive effects by inhibiting the release of various cytokines.
ATC Classification	D07AC19 - difluprednate ; Belongs to the class of potent (group III) corticosteroids. Used in the treatment of dermatological diseases.
Available As	Difluprednate 0.05% w/v

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