Indications |
Oral Allergic and inflammatory disorders Adult: Initially, up to 120 mg daily. Maintenance: 3-18 mg/day. Child: 0.25-1.5 mg/kg/day given on alternate days. Hepatic impairment: Dose reductions may be needed. |
Contraindications |
Systemic infection; live virus vaccines in those receiving immunosuppressive doses. |
Warnings / Precautions |
Adrenal suppression and infection, child, adolescents, elderly, history of TB and steroid myopathy, hypertension, recent MI, CHF, liver failure, renal impairment, DM and glaucoma (including family history), osteoporosis, corneal perforation, severe affective disorders, epilepsy, peptic ulcer, hypothyroidism, pregnancy and lactation. |
Adverse Reactions |
GI disturbances, musculoskeletal, endocrine, neuropsychiatric, ophthalmic, fluid and electrolyte disturbances; susceptible to infection, impaired healing, hypersensitivity, skin atrophy, striae, telangiectasia, acne, myocardial rupture following recent MI, thromboembolism. |
Drug Interactions |
Antacids, ACE inhibitors, acetazolamide, adrenergic neuron blockers, antidiabetics, aspirin, barbiturate, β-blockers, calcium-channel blockers, carbamazepine, carbenoxolone, cardiac glycosides, clonidine, coumarins, diazoxide, diuretics, erythromycin, hydralazine, ketoconazole, methotrexate, methyldopa, mifepristone, minoxidil, moxonidine, nitrates, nitroprusside, NSAIDs, oestrogens, phenytoin, primidone, rifamycins, ritonavir, somatropin, β2 sympathomimetics, theophylline, vaccines. See Below for More deflazacort Drug Interactions |
Food Interactions |
Salad and vegetable diet including alcohol may affect anticoagulant control. |
Mechanism of Actions |
Deflazacort, derived from prednisolone, is a corticosteroid with mainly glucocorticoid activity. An anti-inflammatory dose of 6 mg deflazacort is equiv to 5 mg prednisolone. |
ATC Classification |
H02AB13 - deflazacort ; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations. |
Available As |
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Deflazacort
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Deflazacort Containing Brands
Deflazacort is used in following diseases
Drug - Drug Interactions of Deflazacort
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