Indications |
Oral As an alkaliniser agent Adult: As sodium citrate and citric acid solution: 10-30 ml after meals and at bedtime. Dosage should be individualised according to patient's response and tolerance. As sodium citrate: 1-2 g every 2-4 hr when necessary. Child: As sodium citrate and citric acid solution: 5-15 ml after meals and at bedtime. Dosage should be individualised according to patient's response and tolerance. |
Contraindications |
Patients on a sodium-restricted diet. Severe renal impairment. Potassium citrate and citric acid oral solution are contraindicated in patients with adynamia episodica hereditaria, acute dehydration, heat cramps, anuria, severe myocardial damage, or hyperkalaemia. |
Warnings / Precautions |
Monitor electrolyte balance and acid-base balance regularly especially in patients with renal disorders. Patients with low urine output, congestive heart failure, hypertension, renal dysfunction, peripheral or pulmonary oedema, or toxaemia of pregnancy. Preparations containing potassium should be used with extreme caution in patients in whom large amount of potassium may have a detrimental effect. |
Adverse Reactions |
Frequent administration or intake of large quantities may cause teeth erosion and have a local irritant effect. |
Drug Interactions |
Oral doses of citrate may increase intestinal absorption of aluminium ions. See Below for More citric acid Drug Interactions |
Mechanism of Actions |
Citrate salts are alkalinisers. They are commonly used in situations where long-term maintenance of an alkaline urine is necessary and in the management of chronic metabolic acidosis. Citric acid is also used in effervescing mixtures and as a synergist to improve the efficacy of antioxidants. It may also be used in preparations that are used in the treatment of dry mouth and to dissolve renal calculi and prevent encrustation of urinary catheters. Metabolism: Citrate salts are largely metabolised. Excretion: <5% of an oral dose is excreted unchanged in the urine. |
ATC Classification |
A09AB04 - citric acid ; Belongs to the class of acid preparations used as digestives. |
Available As |
|
Citric Acid
Post Review about Citric Acid Click here to cancel reply.
Citric Acid Containing Brands
Citric Acid is used in following diseases
Drug - Drug Interactions of Citric Acid
Latest News
- FDA approves Ruconest for treatment of hereditary angioedema
- FDA recommend against aspirin to prevent First Heart Attacks
- FDA approves Pomalyst (pomalidomide) for advanced multiple myeloma
- FDA approves three new drug treatments for type 2 diabetes
- Long-term consequences of vaginal delivery on the pelvic floor
No comments yet.