Choline Theophylline

Indications
Oral
Reversible airways obstruction
Adult: Initially, 0.2-0.4 g daily and increase gradually according to response. Maintenance: 0.8-1.2 g daily in 3-4 divided doses.
Child: 10-14 yrs: 400-800 mg in 4 divided doses; 5-9 yrs: 200-400 mg in 4 divided doses; <5 yrs: 24-36 mg/kg body weight/day in 3 divided doses.
Warnings / Precautions
Peptic ulceration, hyperthyroidism, hypertension, cardiac arrhythmias or other CV diseases, epilepsy, hepatic dysfunction, chronic alcoholism, acute febrile illness; smoking; neonates; elderly; pregnancy, lactation.
Adverse Reactions
GI irritation and disturbances, CNS stimulation, headache, anxiety, restlessness, dizziness, tremor, palpitations.
Drug Interactions
Xanthines (additive effects), allopurinol, some antiarrhythmics, cimetidine, disulfiram, fluvoxamine, interferon-α, macrolide antibacterials, quinolones, oral contraceptives, tiabendazole, viloxazine, anticonvulsants, ritonavir, rifampicin, sulfinpyrazone, halothane, ketamine, β-blockers.
See Below for More choline theophyllinate Drug Interactions
Mechanism of Actions
Choline theophyllinate is a theophylline salt which liberates theophylline in the body. It inhibits the activity of phosphodiesterase, resulting in the intracellular accumulation of cyclic adenosine monophosphate (cAMP), thus leading to bronchodilation.
ATC Classification
R03DA02 - choline theophyllinate ; Belongs to the class of xanthines. Used in the systemic treatment of obstructive airway diseases.
Available As
  • Choline Theophylline 100 mg
  • Choline Theophyllinate 100 mg
  • Choline Theophyllinate 157.23 mg
  • Choline Theophyllinate 314.46 mg
  • Choline Theophylline 50 mg
  • Choline Theophyllinate 50 mg
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