Chlorpheniramine

Indications
Oral
Allergic conditions
Adult: 4 mg every 4-6 hr. Max: 24 mg daily.
Child: 1-2 yr: 1 mg bid, 2-5 yr: 1 mg every 4-6 hr, 6-12 yr: 2 mg every 4-6 hr. Max: 6 mg daily (1-5 yr); 12 mg daily (6-12 yr).
Parenteral
Adjunct in the emergency treatment of anaphylactic shock
Adult: 10-20 mg IM, SC, or slow IV inj over 1 min. Max dose: 40 mg daily.
Child: 87.5 mcg/kg SC 4 times daily

Incompatibility: Incompatible with calcium chloride, kanamycin sulfate, noradrenaline acid tartrate, pentobarbital sodium and meglumine adipiodone.
Incompatibility: Incompatible with calcium chloride, kanamycin sulfate, noradrenaline acid tartrate, pentobarbital sodium and meglumine adipiodone.
Contraindications
Hypersensitivity, neonates.
Warnings / Precautions
Elderly, pylori duodenal obstruction, angle-closure glaucoma, urinary retention, prostatic hyperplasia, epilepsy, renal and hepatic impairment. May affect performance of skilled tasks. BPH, bladder neck obstruction, hypertension. Pregnancy, lactation.
Adverse Reactions
CNS depression, sedation, drowsiness, lassitude, dizziness. GI upsets, anorexia, or increased appetite, epigastric pain, blurring of vision, dysuria, dryness of mouth, tightness in chest, hypotension, muscular weakness, tinnitus, euphoria, headache, paradoxical CNS stimulation.
Potentially Fatal: CV collapse and respiratory failure.
Drug Interactions
Potentiates sedative effect of psychotropic drugs e.g. barbiturates, hypnotics, opioid analgesics, anxiolytics and antipsychotics. Interaction with alcohol could be dangerous (sedation/excitation).
See Below for More chlorphenamine Drug Interactions
Food Interactions
Reduced bioavailability
Mechanism of Actions
Chlorphenamine is an H1-receptor antagonist which competetively blocks H1-receptor sites on tissues.
Duration: 4-6 hr.
Absorption: Absorbed relatively slowly from the GI tract (oral); peak plasma concentrations after 2.5-6 hr.
Distribution: Widely distributed; CNS. Protein-binding: 70%.
Metabolism: Extensive; converted to desmethyl- and didesmethylchlorphenamine.
Excretion: Via urine (as unchanged drug and metabolites).
Administration
May be taken with or without food.
Storage Conditions
Oral: Store below 25°C. Parenteral: Store below 25°C.
ATC Classification
R06AB04 - chlorphenamine ; Belongs to the class of substituted alkylamines used as systemic antihistamines.
Storage
Oral: Store below 25°C. Parenteral: Store below 25°C.
Available As
  • Chlorpheniramine Maleate 0.01%
  • Chlorpheniramine Maleate 0.01% w/v
  • Chlorpheniramine Maleate 0.02% w/v
  • Chlorpheniramine Maleate 0.03% w/v
  • Chlorpheniramine Maleate 0.1 mg
  • Chlorpheniramine Maleate 0.1%
  • Chlorpheniramine Maleate 0.1% w/v
  • Chlorpheniramine Maleate 0.2 % w/v
  • Chlorpheniramine 0.2%
  • Chlorpheniramine Maleate 0.2% w/v
  • Chlorpheniramine Maleate 0.2% w/w
  • Chlorpheniramine Maleate 0.4% w/v
  • Chlorpheniramine Maleate 0.5 mg
  • Chlorpheniramine Maleate 1 mg
  • Chlorpheniramine 1 mg
  • Chlorpheniramine 1.25 mg
  • Chlorpheniramine Maleate 1.25 mg
  • Chlorpheniramine Maleate 1.5 mg
  • Chlorpheniramine 10 mg
  • Chlorpheniramine Maleate 10 mg
  • Chlorpheniramine Maleate 100 mg
  • Chlorpheniramine 100 mg
  • Chlorpheniramine Maleate 15 mg
  • Chlorpheniramine Maleate 2 mg
  • Chlorpheniramine 2 mg
  • Chlorpheniramine Maleate 2 mg, 4 mg
  • Chlorpheniramine Maleate 2.0 mg
  • Chlorpheniramine Maleate 2.5 mg
  • Chlorpheniramine 2.5 mg
  • Chlorpheniramine Maleate 2.54 mg
  • Chlorpheniramine Maleate 20 mg
  • Chlorpheniramine Maleate 2mg
  • Chlorpheniramine Maleate 3 mg
  • Chlorpheniramine 3 mg
  • Chlorpheniramine Maleate 4 mg
  • Chlorpheniramine 4 mg
  • Chlorpheniramine Maleate 4. 5 mg
  • Chlorpheniramine Maleate 4.0 mg
  • Chlorpheniramine Maleate 4mg
  • Chlorpheniramine Maleate 5 mg
  • Chlorpheniramine Maleate 6 mg
  • Chlorpheniramine Maleate 8 mg
  • Chlorpheniramine 8 mg
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    One Response to Chlorpheniramine

    1. Dr Khizar Abdullah August 27, 2013 at 3:56 pm #

      I hav developed chest pain after taking tab Chlorpheniramine(piriton). I want to know whether it will resolve or not. 13-hrs have passed but the pain persists.

    Post Review about Chlorpheniramine

     


    Chlorpheniramine Containing Brands

    Click on Prescription information to see Indications ( Uses ), Contraindications, Prescription information of respective Constituents.

    Brand Name Manufacturer Unit/Price Package unit/Price Constituents/Unit
    Tablet Active (400+2)
    Acichem Laboratories 1 Tablet
    ₹ 0.21
    1000 Table
    ₹ 210.00
  • More Information Chlorpheniramine Maleate 2 mg
  • More Information Paracetamol 400 mg
  • See Brands having above combination
    Tablet Active 2 (500+2)
    Acichem Laboratories 1 Tablet
    ₹ 0.24
    1000 Table
    ₹ 240.00
  • More Information Paracetamol 500 mg
  • More Information Chlorpheniramine Maleate 2 mg
  • See Brands having above combination
    Tablet Abalgin (500+50+2)
    Vostok & Wilcure Remedies 1 Tablet
    ₹ 0.90
    10 Tablet
    ₹ 9.00
  • More Information Paracetamol 500 mg
  • More Information Chlorpheniramine Maleate 2 mg
  • More Information Caffeine 50 mg
  • See Brands having above combination
    Tablet Chlorpheniramine (4 mg)
    Shalaks Pharmaceuticals Pvt. Ltd. 1 Tablet
    ₹ 0.72
    10 Tablet
    ₹ 7.16
  • More Information Chlorpheniramine Maleate 4 mg
  • See Brands having above combination
    Tablet Chlorpheniramine (4 mg) (Agron)
    Agron Remedies Pvt Ltd 1 Tablet
    ₹ 0.52
    100 Tablet
    ₹ 52.00
  • More Information Chlorpheniramine Maleate 4 mg
  • See Brands having above combination
    Tablet Chlorpheniramine (4 mg) (Shalina)
    Shalina Laboratories Ltd 1 Tablet
    ₹ 0.50
    10 Tablet
    ₹ 5.00
  • More Information Chlorpheniramine Maleate 4 mg
  • See Brands having above combination
    Tablet Chlorpheniramine (4 mg) (Smith)
    Smith Stanistreet Pharmaceuticals Ltd. 1 Tablet
    ₹ 0.44
    100 Tablet
    ₹ 44.00
  • More Information Chlorpheniramine Maleate 4 mg
  • See Brands having above combination
    Injection Chlorpheniramine Maleate (300 mg)
    Paksons Pharmaceuticals (P) Ltd. 1 ml
    ₹ 0.52
    30 ml
    ₹ 15.62
  • More Information Chlorpheniramine Maleate 10 mg
  • See Brands having above combination
    Tablet Chlorpheniramine Maleate (4 mg)
    Acichem Laboratories 1 Tablet
    ₹ 0.40
    100 Tablet
    ₹ 40.00
  • More Information Chlorpheniramine Maleate 4 mg
  • See Brands having above combination
    Tablet Chlorpheniramine Maleate (4 mg) (Bini)
    Bini Laboratories Pvt Ltd 1 Tablet
    ₹ 0.35
    10 Tablet
    ₹ 3.50
  • More Information Chlorpheniramine Maleate 4 mg
  • See Brands having above combination
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    Chlorpheniramine is used in following diseases

    We are Developing Our database, More results coming soon.

    Pages: 1 2 3 4 5 6 7 8 ... 98 99 100 Next
    Drug - Drug Interactions of Chlorpheniramine
    Interaction
    Moderate, Consider therapy modification Dihydrocodeine, chlorpheniramine, and phenylephrine vs Tricyclic Antidepressants
    Minor, Monitor Therapy Dihydrocodeine, chlorpheniramine, and phenylephrine vs Tocilizumab
    Minor, Monitor Therapy Dihydrocodeine, chlorpheniramine, and phenylephrine vs Thiazide Diuretics
    Minor, Monitor Therapy Dihydrocodeine, chlorpheniramine, and phenylephrine vs Sympathomimetics
    Minor, Monitor Therapy Dihydrocodeine, chlorpheniramine, and phenylephrine vs Succinylcholine
    Minor, Monitor Therapy Dihydrocodeine, chlorpheniramine, and phenylephrine vs Selective Serotonin Reuptake Inhibitors
    Moderate, Consider therapy modification Dihydrocodeine, chlorpheniramine, and phenylephrine vs QuiNIDine
    Moderate, Consider therapy modification Dihydrocodeine, chlorpheniramine, and phenylephrine vs Pramlintide
    Minor, Monitor Therapy Dihydrocodeine, chlorpheniramine, and phenylephrine vs Pegvisomant
    Minor, Monitor Therapy Dihydrocodeine, chlorpheniramine, and phenylephrine vs Peginterferon Alfa-2b
    Pages: 1 2 3 4 5 6 7 8 ... 74 75 76 Next