Calcium Phosphate

Indications
Oral
Dietary supplement
Adult: Expressed in terms of elemental calcium: 19-50 yr: 1000 mg/day and >50 yr: 1200 mg/day.
Child: Expressed in terms of elemental calcium: 0-6 mth: 210 mg/day; 7-12 mth: 270 mg/day; 1-3 yr: 500 mg/day; 4-8 yr: 800 mg/day; 9-18 yr: 1300 mg/day.
Contraindications
Conditions associated with hypercalcaemia and hypercalciuria.
Warnings / Precautions
Renal impairment (frequent monitoring of serum calcium and phosphorus is recommended); sarcoidosis; history of nephrolithiasis. Avoid IV admin of calcium in patients on cardiac glycosides. Increased risk of hypercalcaemia and hypercalciuria in hypoparathyroid patients receiving high doses of vitamin D. Caution when used in patients with history of kidney stones. Patients should be advised to administer vitamin D concurrently to optimise calcium absorption. Pregnancy.
Adverse Reactions
Gi discomfort e.g. constipation, nausea, vomiting, bloating and gas. Dry mouth, hypercalcaemia, hypophosphataemia, milk-alkali syndrome.
Drug Interactions
May reduce the efficacy of calcium-channel blockers. Concurrent admin of IV calcium salt with cardiac glycosides may lead to serious adverse events. Increased risk of hypercalcaemia when used with thiazide diuretics. May reduce absorption of tetracycline, alendronate, atenolol, iron, quinolone antibiotics, sodium fluoride and zinc.
See Below for More calcium phosphate Drug Interactions
Food Interactions
Increased risk of osteoporosis with ethanol.
Mechanism of Actions
Calcium phosphate is used to prevent or treat negative calcium balance. It prevents or reduces the rate of bone loss. The calcium in calcium salts aids in nerve and muscle performance and allows normal cardiac function.
Absorption: Absorbed largely from the small intestine by active transport and passive diffusion.
Distribution: Crosses the placenta and is distributed into breast milk.
Excretion: Excess calcium is mainly excreted renally. Unabsorbed calcium is removed in the faeces, along with that secreted in the bile and pancreatic juice.
ATC Classification
A12AA01 - calcium phosphate ; Belongs to the class of calcium-containing preparations. Used as dietary supplements.
Available As
  • Calcium Phosphate 0.24 gm
  • Calcium Phosphate 0.240 gm
  • Calcium Phosphate 0.4 gm
  • Calcium Phosphate 0.5%
  • Calcium Phosphate 1.5 gm
  • Calcium Phosphate 100 mg
  • Calcium Phosphate 12 mg
  • Calcium Phosphate 129 mg
  • Calcium Phosphate 130 mg
  • Calcium Phosphate 1330 mg
  • Calcium Phosphate 150 mg
  • Calcium Phosphate 162 mg
  • Calcium Phosphate 18 mg
  • Calcium Phosphate 200 mg
  • Calcium Phosphate 240 mg
  • Calcium Phosphate 3.43 gm
  • Calcium Phosphate 30 mg
  • Calcium Phosphate 300 mg
  • Calcium Phosphate 4 mg
  • Calcium Phosphate 40 mg
  • Calcium Phosphate 480 mg
  • Calcium Phosphate 58 mg
  • Calcium Phosphate 75 mg
  • Calcium Phosphate 82 mg
  • Calcium Phosphate 93.16 mg
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