Indications |
Oral Antacid Adult: Up to 1 g daily. Oral Hyperphosphataemia in patients with chronic renal failure Adult: Dose is adjusted to the individual patient's requirement. Up to 10 g/day may be given in divided doses with meals. Max Dosage: 10 g daily in divided doses. |
Contraindications |
Hypersensitivity to aluminium salts. |
Warnings / Precautions |
Chronic renal impairment; CHF; oedema; cirrhosis and low Na diets; patients with recent GI haemorrhage. Administer 2-3 hrs before/after another medication to minimise drug interactions. Pregnancy and lactation. |
Adverse Reactions |
Constipation; intestinal obstruction (with large doses); phosphate depletion may occur with prolonged admin or large doses. |
Drug Interactions |
Enhanced absorption with citrates or ascorbic acid. Decreases absorption of allopurinol, tetracyclines, quinolones, cephalosporins, biphosphonate derivatives, corticosteroids, cyclosporin, delavirdine, Fe salts, imidazole antifungals, isoniazid, mycophenolate, penicillamine, phosphate supplements, phenytoin, phenothiazines, trientine. See Below for More aluminium hydroxide Drug Interactions |
Food Interactions |
Food decreases gastric emptying time. |
Mechanism of Actions |
Alumunium hydroxide acts on the HCl in the stomach by neutralization, forming aluminium chloride salt and water. Absorption: Alumunium hydroxide reacts with hydrochloric acid in the stomach to form soluble aluminium chloride, which is absorbed from the GI tract. Excretion: Absorbed aluminium is excreted via the urine. Insoluble aluminium salts formed in the intestines, eg, hydroxides, carbonates, phosphates and fatty acid derivatives, are excreted in the faeces. |
Administration |
May be taken with or without food. |
ATC Classification |
A02AB01 - aluminium hydroxide ; Belongs to the class of aluminium-containing antacids. |
Available As |
|
Aluminium Hydroxide
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Aluminium Hydroxide Containing Brands
Aluminium Hydroxide is used in following diseases
Drug - Drug Interactions of Aluminium Hydroxide
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