Aluminium Hydroxide

Indications
Oral
Antacid
Adult: Up to 1 g daily.
Oral
Hyperphosphataemia in patients with chronic renal failure
Adult: Dose is adjusted to the individual patient's requirement. Up to 10 g/day may be given in divided doses with meals.
Max Dosage: 10 g daily in divided doses.
Contraindications
Hypersensitivity to aluminium salts.
Warnings / Precautions
Chronic renal impairment; CHF; oedema; cirrhosis and low Na diets; patients with recent GI haemorrhage. Administer 2-3 hrs before/after another medication to minimise drug interactions. Pregnancy and lactation.
Adverse Reactions
Constipation; intestinal obstruction (with large doses); phosphate depletion may occur with prolonged admin or large doses.
Drug Interactions
Enhanced absorption with citrates or ascorbic acid. Decreases absorption of allopurinol, tetracyclines, quinolones, cephalosporins, biphosphonate derivatives, corticosteroids, cyclosporin, delavirdine, Fe salts, imidazole antifungals, isoniazid, mycophenolate, penicillamine, phosphate supplements, phenytoin, phenothiazines, trientine.
See Below for More aluminium hydroxide Drug Interactions
Food Interactions
Food decreases gastric emptying time.
Mechanism of Actions
Alumunium hydroxide acts on the HCl in the stomach by neutralization, forming aluminium chloride salt and water.
Absorption: Alumunium hydroxide reacts with hydrochloric acid in the stomach to form soluble aluminium chloride, which is absorbed from the GI tract.
Excretion: Absorbed aluminium is excreted via the urine. Insoluble aluminium salts formed in the intestines, eg, hydroxides, carbonates, phosphates and fatty acid derivatives, are excreted in the faeces.
Administration
May be taken with or without food.
ATC Classification
A02AB01 - aluminium hydroxide ; Belongs to the class of aluminium-containing antacids.
Available As
  • Aluminium Hydroxide 0.025% w/w
  • Aluminium Hydroxide 0.215 gm
  • Aluminium Hydroxide 0.25% w/w
  • Aluminium Hydroxide 0.291 gm
  • Aluminium Hydroxide 1.5 gm
  • Aluminium Hydroxide 1.5% w/v
  • Aluminium Hydroxide 1.567 gm
  • Aluminium Hydroxide 1.57 gm
  • Aluminium Hydroxide 100 mg
  • Aluminium Hydroxide 125 mg
  • Aluminium Hydroxide 150 mg
  • Aluminium Hydroxide 153 mg
  • Aluminium Hydroxide 20 mg
  • Aluminium Hydroxide 200 mg
  • Aluminium Hydroxide 240 mg
  • Aluminium Hydroxide 250 mg
  • Aluminium Hydroxide 291 mg
  • Aluminium Hydroxide 300 mg
  • Aluminium Hydroxide 380 mg
  • Aluminium Hydroxide 400 mg
  • Aluminium Hydroxide 426 mg
  • Aluminium Hydroxide 475 mg
  • Aluminium Hydroxide 5 gm
  • Aluminium Hydroxide 500 mg
  • Aluminium Hydroxide 6 gm
  • Aluminium Hydroxide 600 mg
  • Aluminium Hydroxide 610 mg
  • Aluminium Hydroxide 75 mg
  • Aluminium Hydroxide 830 mg
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    Aluminium Hydroxide is used in following diseases

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