Indications |
Oral Threatened miscarriage Adult: 5 mg tid for 5-7 days. |
Contraindications |
Hypersensitivity; thrombophleobitis; undiagnosed vag bleeding, incomplete abortion, hormone-dependent carcinoma, cerebral apoplexy, as a diagnostic test for pregnancy; severe hepatic impairment; pregnancy. |
Warnings / Precautions |
Discontinue medications if there is sudden partial or complete loss of vision, proptosis or diplopia; migraine and embolic disorders; epilepsy, migraine, asthma, cardiac or renal dysfunction. History of depression, glucose tolerance and diabetic patients. My impair ability to drive operate machinery. Sudden withdrawal of allyloestrenol should be avoided as it leads to intermittent breakthrough bleeding; lactation. |
Adverse Reactions |
GI disturbances, appetite/weight change; fluid retention, oedema; acnes, skin rash, urticaria; depression, headache, fever, fatigue; breast changes, hirsutism, changes in libido, altered menstrual cycles or irregular menstrual bleeding (rare). |
Drug Interactions |
Enhanced clearance with enzyme-inducing drugs eg, carbamazepine, griseofulvin, phenobarbital, phenytoin and rifampicin. Ketoconazole may increase bioavailability of progesterone. Potentially Fatal: Increased ciclosporin concentration. See Below for More allylestrenol Drug Interactions |
Lab Interactions |
Alterations in lipid profile and liver function tests. |
Mechanism of Actions |
Allylestrenol is similar to that of natural progesterone. It prepares the uterus for receiving the fertilised ovum and suppresses uterine motility. |
Administration |
May be taken with or without food. (May be taken w/ meals if GI upset occurs.) |
ATC Classification |
G03DC01 - allylestrenol ; Belongs to the class of estren derivative progestogens used in progestogenic hormone preparations. |
Available As |
|
Allylestrenol
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Allylestrenol Containing Brands
Allylestrenol is used in following diseases
Drug - Drug Interactions of Allylestrenol
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